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This study investigates these properties using a p-chlorophenylalanine (PCPA) -induced insomnia model in mice, an approach akin to traditional methods evaluating sleep-promoting activities in fusion peptides
The FDA-approved dosing schedule includes a gradual titration strategy specifically designed to minimize gastrointestinal side effects, starting at 2.5 mg weekly and increasing every four weeks as tolerated
Collectively, these results indicate a beneficial effect of treatment on overall patient health
Plant Growth Regul 46:209221 Shi H, Chen L, Ye T, Liu X, Ding K, Chan Z (2014) Modulation of auxin content in Arabidopsis confers improved drought stress resistance
Most side effects are temporary and manageable
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